Hyperthermic intraperitoneal chemotherapy / HIPEC treatment (also referred to as “heated chemotherapy“) is the name of an innovative method of therapy, developed for treating carcinomas that have metastasized into the abdominal cavity (i.e. ovarian and intestinal cancers, etc.). It helps combat these kinds of metastases and has been shown to significantly prolong patients’ lives.
During heated chemotherapy a highly-concentrated warmed up chemotherapy solution is introduced directly into the abdominal cavity immediately following a cytoreductive surgery. Unlike traditional chemotherapy agents, which circulate through the blood, HIPEC affects the malignant cells in the abdominal cavity directly. This allows for treatment with higher doses. Heating the solution to 42°C is done to improve its absorption by tumour cells and facilitate the destruction of microscopic cells remaining following the surgery.
Before performing the HIPEC, a surgeon will perform a cytoreductive operation, during which he will resect any visible abdominal masses). Once this stage is complete a heated sterilized chemotherapy solution (42°C) is introduced into the abdominal cavity. It is left in the abdomen for 90 minutes.
Heated chemotherapy is indicated for advanced superficial cancers (carcinomatosis) limited to the abdomen. It is performed immediately following surgery in order to destroy all remaining malignant cells, including those that cannot be visualized.
The following diagnostic procedures are required before heated chemotherapy can be scheduled:
Heated chemotherapy cost includes 5 days of hospitalization. You should be able to travel home 15 days after the procedure. Presently HIPEC treatment is available in 3 Israeli medical centers: Assuta Hospital, Chaim Sheba Medical Center and Herzliya Medical center